Cap Analog Comparison: Find the Best Fit for Your mRNA Research
Which cap analog is the best fit for you?
At Areterna, we provide cutting-edge cap analog solutions to enhance mRNA stability, translation efficiency, and therapeutic effectiveness. Our range of cap analogs ensures flexibility and optimization for various applications, including self-amplifying RNA (saRNA) and mRNA vaccines.
Why Choose Areterna Cap Analogs?
✅ License-free for flexible research and commercialization
✅ Available in Research Use Only (RUO) and Good Manufacturing Practice (GMP) grades
✅ Designed for superior mRNA stability and translation efficiency
CAP3011
m7G(5')ppp(5')(2'OMeA)pG- Template Start: AG
- Cap Innovation: m7GpppmApG.
- Application: mRNA
CAP5011 (ENE)
m7G(5')vppp(5')(2'OMeA)pG- Template Start: AG
- Cap Innovation: Vinylphosphonic acid modification (ENE) of linkage between m7G cap and 1st ribonucleic acid.
- Application: mRNA
CAP2811 (3'OMe)
m7(3'OMeG)(5')vppp(5')(2'-OMeA)pG- Template Start: AG
- Cap Innovation: CAP5011 with 3’OMe modification on m7G.
- Application: mRNA
CAP3411 (m6A)
m7(3'OMeG)(5')vppp(5')(2'-OMe,m6A)pG- Template Start: AG
- Cap Innovation: CAP5011 with m6A modification on Base A and 3’OMemodification on m7G.
- Application: mRNA
CAP1811 (GAU)
m7G(5')vppp(5')(2'OMeA)pU- Template Start: AU
- Cap Innovation: CAP5011 with AU start instead of AG.
- Application: saRNA

Choose the right cap analog for your application
Interested in learning more about how Areterna cap analogs can optimize your mRNA research?
Reach out to our sales team at sales@areterna.com for more details or download our comprehensive PDF comparison guide today!