CAP1811 for self-amplifying RNA (saRNA)

Featured Product –

CAP m7G(5′)vppp(5′)(2’OMeA)pU
100mM Ammonium Solution

Category mRNAs: Cap Analog
Product Name CAP m7G(5′)vppp(5′)(2’OMeA)pU
100mM Ammonium Solution

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Product Description

CAP1811 is specifically designed for self-amplifying RNAs based on the genomes of positive sense strand RNA viruses such as
Venezuelan equine encephalitis virus (VEEV), Semliki forest virus (SFV), and Sindbis virus (SIN).

Areterna’s novel CAP1811 is different from commercial cap analogs of AU. CAP1811 is not limited by patents and comparable to AU in
saRNA transcription yield, integrity, capping rate. In addition, the resulting protein expression from the saRNA is high.

High performance & Cost effective. GMP-grade available

Independent intellectual property rights with no patent restrictions

High saRNA protein expression

Ordering Information

 

Cat. No. Size
CAP1811-0.1 100 μL
CAP1811-1 1 mL
CAP1811-10 10 mL
CAP1811-100
100 mL
CAP1811-500
500 mL

 

Recommended IVT Condition

 

Component Volume
10×Transcription Buffer 2 μl
CAP1811(100mM) 2 μl
ATP/CTP/GTP/UTP(100mM each) 2 μl each
T7 RNA Polymerase(250 U/μL) 1 μl
Inorganic Pyrophosphatase(1 U/μL) 0.04 μl
Murine RNase inhibitor (40 U/μL) 1 μl
DNA Template 1 μg
RNase free H2O Up to 20 μl